Devesh Tewari Lab - Fenugreek (Trigonella foenum-graecum L.) Seeds

Journal article

Devesh Tewari, A. Jóźwik, Małgorzata Łysek-Gładysińska, W. Grzybek, W. Adamus-Białek, J. Bicki, N. Strzałkowska, A. Kaminska, Olaf K. Horbańczuk, A. Atanasov
Nutrients, 2020

Semantic Scholar DOI PubMedCentral PubMed

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APA Click to copy
Tewari, D., Jóźwik, A., Łysek-Gładysińska, M., Grzybek, W., Adamus-Białek, W., Bicki, J., … Atanasov, A. (2020). Fenugreek (Trigonella foenum-graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice. Nutrients.

Chicago/Turabian Click to copy
Tewari, Devesh, A. Jóźwik, Małgorzata Łysek-Gładysińska, W. Grzybek, W. Adamus-Białek, J. Bicki, N. Strzałkowska, A. Kaminska, Olaf K. Horbańczuk, and A. Atanasov. “Fenugreek (Trigonella Foenum-Graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice.” Nutrients (2020).

MLA Click to copy
Tewari, Devesh, et al. “Fenugreek (Trigonella Foenum-Graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice.” Nutrients, 2020.

BibTeX Click to copy

@article{devesh2020a,
  title = {Fenugreek (Trigonella foenum-graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice},
  year = {2020},
  journal = {Nutrients},
  author = {Tewari, Devesh and Jóźwik, A. and Łysek-Gładysińska, Małgorzata and Grzybek, W. and Adamus-Białek, W. and Bicki, J. and Strzałkowska, N. and Kaminska, A. and Horbańczuk, Olaf K. and Atanasov, A.}
}

Abstract

Fenugreek seeds are widely used in Asia and other places of the world for their nutritive and medicinal properties. In Asia, fenugreek seeds are also recommended for geriatric populations. Here, we evaluated for the first time the effect of fenugreek seed feed supplementation on the liver antioxidant defense systems in aging mice. The study was conducted on 12-months aged mice which were given fenugreek seed dietary supplement. We evaluated the activities of various antioxidant defense enzymes such as superoxide dismutase (SOD), glutathione reductase (GR), and glutathione peroxidase (GPx), and also estimated the phenolics and free radical scavenging properties in mice liver upon fenugreek supplementation. The estimation of SOD, GPx, and GR activities in aged mice liver revealed a significant (p < 0.01) difference among all the liver enzymes. Overall, this study reveals that fenugreek seed dietary supplementation has a positive effect on the activities of the hepatic antioxidant defense enzymes in the aged mice.